Parents often ask if they should premedicate their baby before immunization in order to prevent fever and discomfort that’s associated with the shots. In fact, a study published last year in The Lancet suggested that acetaminophen (the active ingredient in Tylenol) blunts the immune system’s response to the vaccines. At GetzWell, where we often vaccinate children on a staggered schedule (fewer vaccines per appointment) and strongly discourage premedication, we rarely see post-vaccine fevers or pain. Additionally, an Italian study involving 450 babies (published in Pediatrics in May 2010), showed that half as many infants who were exclusively breastfed developed post-vaccine fevers compared to babies who weren’t breastfed at all. Yet another reason to support breastfeeding whenever possible!